Description

Ethyl 5-Fluoro-2,3-Dihydroindene-1-Acetate is a high-value fluorinated indane derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring a fluorine substituent and an ester functional group, makes it indispensable for constructing complex pharmacophores and fine-tuning material properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Versatile intermediate for further functionalization, including hydrolysis to the corresponding acid, reduction, or cross-coupling reactions.
• Academic & Contract Research: Essential reagent for methodological development and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	Ethyl 5-Fluoro-2,3-Dihydroindene-1-Acetate
CAS No.	904290-44-4
Molecular Formula	C₁₃H₁₅FO₂
Molecular Weight	222.26 g/mol
Synonyms	Ethyl (5-Fluoro-2,3-dihydro-1H-inden-1-yl)acetate; 1H-Indene-1-acetic acid, 5-fluoro-2,3-dihydro-, ethyl ester; 5-Fluoro-2,3-dihydro-1H-indene-1-acetic acid ethyl ester; Ethyl 5-fluoroindane-1-acetate; 904290-44-4; 5-Fluoroindan-1-ylacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Fluoro-2,3-Dihydroindene-1-Acetate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.