Description

2-([1,1'-Biphenyl]-4-Yloxy)-5-(Trifluoromethyl)-Aniline is a specialized aromatic amine derivative featuring a biphenyl ether linkage and a trifluoromethyl substituent. This compound is a high-value pharmaceutical intermediate and organic synthesis building block, prized for its unique structural motifs that can impart desirable properties to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for the development of specialty chemicals used in electronic displays and organic light-emitting diodes (OLEDs) due to its rigid biphenyl core.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the production of high-performance polymers with specific thermal or optical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial research in organic chemistry, facilitating the exploration of new reactions and molecular architectures.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the amine group allows for further functionalization and color tuning.

Basic Information

Product Name	2-([1,1'-Biphenyl]-4-Yloxy)-5-(Trifluoromethyl)-Aniline
CAS No.	904253-69-6
Molecular Formula	C19H14F3NO
Molecular Weight	329.32 g/mol
Synonyms	2-([1,1'-Biphenyl]-4-yloxy)-5-(trifluoromethyl)benzenamine; 2-(Biphenyl-4-yloxy)-5-(trifluoromethyl)aniline; 5-(Trifluoromethyl)-2-(4-phenylphenoxy)aniline; 2-(4-Phenylphenoxy)-5-(trifluoromethyl)aniline; 2-([1,1'-Biphenyl]-4-Yloxy)-5-(Trifluoromethyl)-Aniline; Biphenyl-4-yloxy trifluoromethyl aniline derivative; 904253-69-6; CAS 904253-69-6
EINECS	Contact for details

Quality Control

Our 2-([1,1'-Biphenyl]-4-Yloxy)-5-(Trifluoromethyl)-Aniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.