Description

3-tert-Butoxycarbonylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid ester crucial for modern synthetic chemistry. This compound serves as a versatile and stable building block, enabling the formation of carbon-carbon bonds under mild conditions via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds common in drug molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and OFETs, where precise molecular structure controls material properties.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules or creating molecular probes for diagnostic and research applications.
• Cross-Coupling Reactions: Specifically designed for use in palladium-catalyzed Suzuki-Miyaura cross-coupling, a cornerstone reaction for forming C-C bonds between aryl and vinyl groups.
• Library Synthesis for Drug Discovery: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening in early-stage drug discovery programs.

Basic Information

Product Name	3-tert-Butoxycarbonylphenylboronic Acid Pinacol Ester
CAS No.	903895-48-7
Molecular Formula	C₁₇H₂₅BO₄
Molecular Weight	304.19 g/mol
Synonyms	3-((tert-Butoxycarbonyl)phenyl)boronic acid pinacol ester; 3-Boc-phenylboronic acid pinacol ester; (3-(tert-Butoxycarbonyl)phenyl)boronic acid pinacol ester; 3-(Boc)phenylboronic acid pinacol ester; 3-Carboxytert-butylphenylboronic acid pinacol ester; Pinacol 3-(tert-butoxycarbonyl)benzeneboronate; 903895-48-7; BCPB pinacol ester.
EINECS	Contact for details

Quality Control

Every batch of 3-tert-Butoxycarbonylphenylboronic Acid Pinacol Ester undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent hydrolysis and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.