Description

3-(2,2,2-Trifluoroethoxy)Benzenemethanamine is a high-purity aromatic amine derivative featuring a trifluoroethoxy substituent, a key structural motif in advanced chemical synthesis. This compound is valued for its role as a versatile and critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoroethoxy group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials with specific optical or electronic properties.
• Fluorinated Compound Library: A key reagent for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated amine.

Basic Information

Product Name	3-(2,2,2-Trifluoroethoxy)Benzenemethanamine
CAS No.	903630-07-9
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	[1-(3-(2,2,2-Trifluoroethoxy)phenyl)methanamine]; (3-(2,2,2-Trifluoroethoxy)phenyl)methanamine; 1-(3-(Trifluoroethoxy)phenyl)methanamine; 3-(Trifluoroethoxy)benzylamine; α-(3-(Trifluoroethoxy)phenyl)methylamine; Benzenemethanamine, 3-(2,2,2-trifluoroethoxy)-; CAS 903630-07-9
EINECS	Contact for details

Quality Control

Our 3-(2,2,2-Trifluoroethoxy)Benzenemethanamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality system is designed to meet the stringent requirements of pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.