Description

2-Formylpyridine-4-Boronic Acid is a versatile bifunctional heterocyclic building block that combines a reactive aldehyde group with a boronic acid moiety. This dual functionality makes it a critical intermediate in modern synthetic chemistry, particularly for constructing complex molecular architectures via sequential cross-coupling and condensation reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: The boronic acid group enables efficient palladium-catalyzed coupling with aryl/heteroaryl halides to create biaryl structures.
• Ligand Synthesis for Catalysis: Used to prepare pyridine-based ligands for transition metal catalysts in asymmetric synthesis and industrial processes.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, light-emitting materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and bioconjugates for diagnostic and research applications.

Basic Information

Product Name	2-Formylpyridine-4-Boronic Acid
CAS No.	903513-63-3
Molecular Formula	C6H6BNO3
Molecular Weight	150.93 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinaldehyde; 2-Pyridinecarboxaldehyde, 4-borono-; 4-Borono-2-pyridinecarboxaldehyde; 2-Formyl-4-pyridineboronic acid; 4-Boronopicolinaldehyde; Picolinaldehyde-4-boronic acid; 4-(Boronyl)picolinaldehyde
EINECS	Contact for details

Quality Control

Our 2-Formylpyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.