Description

4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-2,6-Dicarbonitrile is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and materials science research. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and the creation of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients for crop protection products.
• Material Science: Precursor for constructing conjugated organic frameworks, ligands for catalysts, and monomers for functional polymers.
• Chemical Research: Versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Ligand Synthesis: Building block for creating sophisticated bidentate and polydentate ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-2,6-Dicarbonitrile
CAS No.	903513-61-1
Molecular Formula	C14H16BN3O2
Molecular Weight	269.11 g/mol
Synonyms	2,6-Dicyano-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Pinacolatoboryl-2,6-pyridinedicarbonitrile; 2,6-Pyridinedicarbonitrile, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-pyridinedicarbonitrile; 4-BPin-2,6-Pyridinedicarbonitrile
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-2,6-Dicarbonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.