Description

2-Bromo-1-Ethylsulfanyl-4-Nitrobenzene CAS NO 900175-18-0 is a specialized organic intermediate featuring a nitro group and a bromine substituent on a benzene ring, further functionalized with an ethylsulfanyl moiety. This unique structure makes it a valuable building block for synthesizing more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, dyes, and functional materials. The compound's reactivity profile allows for selective transformations, enabling the construction of diverse chemical libraries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those requiring a nitroarene or aryl bromide for further coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the nitro and sulfur-containing groups contribute to biological activity.
• Dye and Pigment Synthesis: Acts as an intermediate for creating specialized azo dyes or other colored compounds due to its electron-withdrawing nitro group.
• Material Science: Employed in the research of organic semiconductors, liquid crystals, or polymers where precise aromatic functionalization is critical.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination to form biaryl or carbon-heteroatom bonds.
• Chemical Biology Probes: Can be utilized to create tagged molecules or affinity probes for studying biological processes.

Basic Information

Product Name	2-Bromo-1-Ethylsulfanyl-4-Nitrobenzene
CAS No.	900175-18-0
Molecular Formula	C8H8BrNO2S
Molecular Weight	262.12 g/mol
Synonyms	1-Bromo-2-(ethylthio)-4-nitrobenzene; 2-Bromo-1-(ethylthio)-4-nitrobenzene; 4-Nitro-2-bromophenyl ethyl sulfide; Benzene, 2-bromo-1-(ethylthio)-4-nitro-; 2-Bromo-4-nitrothioanisole (ethyl analog); Ethyl 2-bromo-4-nitrophenyl sulfide; 2-(Ethylsulfanyl)-1-bromo-4-nitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Ethylsulfanyl-4-Nitrobenzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques such as HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.