Description

3,3'-Dithiodipropionic Acid is a versatile sulfur-containing dicarboxylic acid that serves as a crucial building block and cross-linking agent in advanced chemical synthesis. Its disulfide bridge enables unique redox-responsive properties and the formation of dynamic covalent bonds, making it valuable for creating smart materials and functional polymers. This compound is essential for researchers and manufacturers in the pharmaceutical, polymer, and cosmetic industries seeking to develop controlled-release systems, self-healing materials, or hair care products.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs and drug delivery systems where a disulfide linkage provides glutathione-responsive release in targeted therapies.
• Polymer & Material Science: Acts as a cross-linker for creating dynamic, redox-responsive hydrogels and self-healing polymers with reversible disulfide bonds.
• Cosmetic & Personal Care: Employed in hair care formulations as a precursor for hair-waving agents and conditioners that modify keratin structure.
• Bioconjugation & Protein Chemistry: Serves as a linker for coupling molecules (e.g., peptides, drugs) to carriers like polymers or nanoparticles via cleavable disulfide bonds.
• Chemical Synthesis: A key starting material for synthesizing dithiols, thioesters, and other organosulfur compounds used in organic and medicinal chemistry.
• Research & Development: Utilized in academic and industrial R&D for studying disulfide exchange reactions and developing novel biomaterials.

Basic Information

Product Name	3,3'-Dithiodipropionic Acid
CAS No.	1119-62-6
Molecular Formula	C6H10O4S2
Molecular Weight	210.27 g/mol
Synonyms	3,3'-Dithiobis(propanoic acid); Bis(2-carboxyethyl) disulfide; β,β'-Dithiodipropionic acid; Propanoic acid, 3,3'-dithiobis-; DTDPA; 4,4'-Dithiobis(butyric acid) (obsolete); NSC 75609; 3,3'-Disulfanediyldipropanoic acid (IUPAC)
EINECS	214-285-4

Quality Control

Our 3,3'-Dithiodipropionic Acid is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay, identification, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can supply material compliant with various customer-specific requirements and support regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.