Description

Thioanisole (CAS NO 100-68-5) is a versatile organosulfur compound widely used as a key building block and intermediate in advanced chemical synthesis. Its primary value lies in its role as a methylthio group donor and its utility in various coupling and functionalization reactions. This high-purity intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it contributes to the production of active ingredients, ligands, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), including antiviral and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the manufacture of pesticides, herbicides, and fungicides as a key sulfur-containing building block.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Organic Synthesis Building Block: Employed in Friedel-Crafts alkylation, cross-coupling reactions (e.g., Suzuki, Heck), and as a source of the thiomethyl group.
• Flavor and Fragrance Industry: Used in the research and development of certain sulfur-containing aroma compounds.
• Material Science Research: Investigated as a monomer or additive in the development of novel polymers and electronic materials.

Basic Information

Product Name	Thioanisole
CAS No.	100-68-5
Molecular Formula	C7H8S
Molecular Weight	124.20 g/mol
Synonyms	Methyl phenyl sulfide; (Methylthio)benzene; Phenyl methyl sulfide; Methylthiobenzene; Benzene, (methylthio)-; Thiomethoxyphenyl; Thiomethylbenzene; Sulfide, methyl phenyl
EINECS	202-878-2

Quality Control

Our Thioanisole is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and minimize evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to standard
Assay (GC)	≥ 98.0%
Refractive Index (n20/D)	1.582 - 1.587
Density (20°C)	1.055 - 1.065 g/mL
Water Content (KF)	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.