Description

4-Bromo-2-Ethoxy-1-Fluorobenzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its unique halogen and ether substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine atoms and bromo/ethoxy functional groups into complex molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motifs can contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating fluorinated aromatic cores in electronic and display materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Organic Synthesis Research: Employed in academic and industrial R&D labs for exploring new reaction pathways and synthesizing complex, functionalized aromatic compounds.
• Fluorine Chemistry Studies: Acts as a model compound for studying the effects of fluorine substitution adjacent to other functional groups on reactivity and physical properties.

Basic Information

Product Name	4-Bromo-2-Ethoxy-1-Fluorobenzene
CAS No.	900174-64-3
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-Bromo-4-ethoxy-3-fluorobenzene; 3-Fluoro-4-bromophenetole; 4-Bromo-2-ethoxyfluorobenzene; 2-Ethoxy-4-bromo-1-fluorobenzene; 4-Bromo-3-fluorophenetole; 1-Fluoro-2-ethoxy-4-bromobenzene; Benzene, 4-bromo-2-ethoxy-1-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Ethoxy-1-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment ensures material consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.