Description

4-Ketopipecolic acid hydrochloride is a high-purity, non-proteinogenic amino acid derivative and a key chiral building block in organic synthesis. This compound matters for its role as a versatile intermediate in the research and development of complex pharmaceutical molecules, particularly those targeting neurological and metabolic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing peptidomimetics and other bioactive compounds.

Application

• Pharmaceutical intermediate for the synthesis of novel drug candidates.
• Chiral building block in asymmetric synthesis and medicinal chemistry research.
• Precursor for the development of protease inhibitors and enzyme modulators.
• Research chemical in neuroscience for studying neurotransmitter analogs.
• Starting material for the preparation of conformationally constrained peptides (peptidomimetics).
• Intermediate in the synthesis of natural product analogs and complex heterocycles.
• Reference standard for analytical method development and quality control.

Basic Information

Product Name	4-Ketopipecolic acid hydrochloride
CAS No.	99979-55-2
Molecular Formula	C6H9NO3·HCl
Molecular Weight	195.60 g/mol
Synonyms	4-Oxopipecolic acid hydrochloride; 4-Oxopipecolate hydrochloride; 2-Piperidinecarboxylic acid, 4-oxo-, hydrochloride (1:1); (RS)-4-Oxopipecolic acid hydrochloride; 4-Ketopipecolate HCl; 4-Piperidone-2-carboxylic acid hydrochloride; 4-Oxo-L-pipecolic acid hydrochloride (if chiral); L-4-Oxopipecolic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Ketopipecolic acid hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.