Description

1H-Azepine-1-Carboxaldehyde, Hexahydro-2-(Hydroxymethyl)- (6Ci) is a specialized heterocyclic building block featuring a seven-membered azepine ring functionalized with both aldehyde and hydroxymethyl groups. This compound matters as a versatile chiral intermediate for the synthesis of complex pharmaceutical molecules and advanced organic materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of central nervous system (CNS) active drugs, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands used in asymmetric catalysis.
• Polymer Chemistry: Building block for specialty polymers and resins, contributing to thermal stability and specific functional properties.
• Academic & Industrial R&D: Essential for methodological studies in organic synthesis and the exploration of new chemical space in medicinal chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex flavors, fragrances, and advanced electronic chemicals.

Basic Information

Product Name	1H-Azepine-1-Carboxaldehyde, Hexahydro-2-(Hydroxymethyl)- (6Ci)
CAS No.	99969-69-4
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	Hexahydro-2-(hydroxymethyl)-1H-azepine-1-carboxaldehyde; 2-(Hydroxymethyl)hexahydro-1H-azepine-1-carbaldehyde; 1-Azepanecarboxaldehyde, 2-(hydroxymethyl)-; 2-(Hydroxymethyl)azepane-1-carbaldehyde; (Hexahydro-1H-azepin-1-yl)(hydroxy)acetaldehyde (tautomer); 1H-Azepine-1-carboxaldehyde, hexahydro-2-(hydroxymethyl)-; 99969-69-4
EINECS	Contact for details

Quality Control

Our 1H-Azepine-1-Carboxaldehyde, Hexahydro-2-(Hydroxymethyl)- (6Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.