Description

2-Hydroxy-3-Iodoaniline is a halogenated aniline derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both an amino and a hydroxyl group ortho to an iodine atom, makes it a critical intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting tyrosine kinase inhibitors and other halogen-containing bioactive molecules.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators where the iodine moiety can enhance biological activity and environmental specificity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-rich aromatic system.
• Chemical Research & Development: Employed as a standard reagent in cross-coupling reactions (e.g., Suzuki, Heck) and for introducing iodine labels in tracer studies and analytical method development.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex azo dyes and pigments where the iodine substituent can alter color fastness and spectral properties.

Basic Information

Product Name	2-Hydroxy-3-Iodoaniline
CAS No.	99968-81-7
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	3-Iodo-2-aminophenol; 2-Amino-3-iodophenol; 3-Iodo-2-hydroxyaniline; 2-Hydroxy-3-iodobenzenamine; o-Amino-o'-iodophenol; 99968-81-7; Benzenamine, 2-hydroxy-3-iodo-
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Iodoaniline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.