Description

(E)-2-Methyl-2-Butenoic Acid (3Ar,6As)-2,3,3Aβ,7Aα,7Bα,8A,8Bβ,8Cα-Octahydro-6,8Aα-Dimethyl-3-Methylene-2-Oxo-4H-Bisoxireno[1,8A:2,3]Azuleno[4,5-B]Furan-4α-Yl Ester is a high-purity, complex organic ester derivative with a defined stereochemistry, serving as a critical advanced intermediate in specialized chemical synthesis. Its intricate, polycyclic structure makes it a valuable building block for constructing novel molecular architectures in research and development. This compound is essential for pharmaceutical chemists and advanced material scientists working on complex natural product analogs, specialty polymers, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents.
• Advanced Material Synthesis: Used in the development of specialty polymers, liquid crystals, and organic electronic materials requiring precise stereochemical control.
• Agrochemical Research: Serves as a precursor in the synthesis of new-generation, structurally complex pesticides and herbicides with enhanced specificity.
• Natural Product Analog Synthesis: Employed as a core fragment in the semi-synthesis or total synthesis of complex natural products and their derivatives for biological evaluation.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes and tags for studying biological mechanisms at the molecular level.
• Catalyst & Ligand Development: Acts as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Item	Details
Product Name	(E)-2-Methyl-2-Butenoic Acid (3Ar,6As)-2,3,3Aβ,7Aα,7Bα,8A,8Bβ,8Cα-Octahydro-6,8Aα-Dimethyl-3-Methylene-2-Oxo-4H-Bisoxireno[1,8A:2,3]Azuleno[4,5-B]Furan-4α-Yl Ester
CAS No.	99956-51-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(E)-2-Methylbut-2-enoic acid (3aR,6aS)-2,3,3aβ,7aα,7bα,8a,8bβ,8cα-octahydro-6,8aα-dimethyl-3-methylene-2-oxo-4H-bisoxireno[1,8a:2,3]azuleno[4,5-b]furan-4α-yl ester; Tiglic Acid (3aR,6aS)-2,3,3aβ,7aα,7bα,8a,8bβ,8cα-Octahydro-6,8aα-Dimethyl-3-methylene-2-oxo-4H-bisoxireno[1,8a:2,3]azuleno[4,5-b]furan-4α-yl Ester; CAS 99956-51-1; 4H-Bisoxireno[1,8a:2,3]azuleno[4,5-b]furan-4α-ol, 2,3,3aβ,7aα,7bα,8a,8bβ,8cα-octahydro-6,8aα-dimethyl-3-methylene-2-oxo-, (2E)-2-methyl-2-butenoate; (E)-2-Methylcrotonic Acid Ester Derivative.
EINECS	Contact for details

Quality Control

Our (E)-2-Methyl-2-Butenoic Acid ester derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically verified by techniques such as HPLC, GC, NMR, and chiral analysis. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and advanced material R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to heat, moisture, and strong oxidizing agents. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.