Description

2-[[(Tetrahydropyran-2-Yl)Oxy]Methyl]Benzaldehyde is a versatile and high-value protected benzaldehyde derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in the tetrahydropyranyl (THP) protecting group, which masks the reactive aldehyde functionality, allowing for selective transformations elsewhere in the molecule under a wide range of reaction conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to construct complex molecular architectures for active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the protected aldehyde allows for the introduction of specific functional groups.
• Fine Chemical Manufacturing: Serves as a precursor for fragrances, flavors, and specialty polymers requiring controlled, multi-step synthetic sequences.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis research.
• Peptide & Carbohydrate Chemistry: The THP-protected aldehyde can be used in conjugation strategies or as a handle for further elaboration in bioconjugate chemistry.
• Material Science: Potential monomer or cross-linking agent in the development of specialty resins and functional polymers.

Basic Information

Product Name	2-[[(Tetrahydropyran-2-Yl)Oxy]Methyl]Benzaldehyde
CAS No.	99948-47-7
Molecular Formula	C₁₃H₁₆O₃
Molecular Weight	220.26 g/mol
Synonyms	2-((Tetrahydro-2H-pyran-2-yloxy)methyl)benzaldehyde; Benzaldehyde, 2-[[(tetrahydro-2H-pyran-2-yl)oxy]methyl]-; 2-(THP-O-Methyl)benzaldehyde; 2-Formylbenzyl tetrahydropyran-2-yl ether; 2-((Tetrahydropyran-2-yloxy)methyl)benzaldehyde; THP-protected 2-formylbenzyl alcohol; 2-Hydroxymethylbenzaldehyde THP ether
EINECS	Contact for details

Quality Control

Our 2-[[(Tetrahydropyran-2-Yl)Oxy]Methyl]Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use as a synthetic intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.