Description

Mesigyna is a synthetic progestogen-estrogen combination used in pharmaceutical formulations. This compound is critical for providing reliable and long-acting hormonal activity in therapeutic applications. It is primarily required by manufacturers in the global pharmaceutical industry for the production of injectable contraceptive and hormone replacement therapies.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of long-acting injectable contraceptive formulations.
• Hormone Replacement Therapy (HRT): Used in combination therapies for managing menopausal symptoms and related conditions.
• Veterinary Pharmaceuticals: Application in animal health for estrus synchronization and reproductive management.
• Research & Development: Serves as a reference standard and key intermediate in endocrine and pharmacological research.
• Formulation Development: Used in the development of novel drug delivery systems, including implants and depot injections.

Basic Information

Product Name	Mesigyna
CAS No.	99897-30-0
Molecular Formula	C28H38O3
Molecular Weight	422.60 g/mol
Synonyms	Norethisterone Enanthate + Estradiol Valerate; Norethindrone Enanthate and Estradiol Valerate; NET-EN/E2V; Norethisterone Enanthate/Estradiol Valerate Combination; Monthly Injectable Contraceptive; Norigynon; HRP-112; SC-4640
EINECS	Contact for details

Quality Control

Our Mesigyna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications, including identity, purity, and potency. Certificates of Analysis (COA) documenting compliance with relevant pharmacopeial standards (e.g., USP, BP, EP) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Description	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.