Description

Mifepristone CAS NO 84371-65-3 is a synthetic steroid compound that acts as a potent antagonist of the progesterone and glucocorticoid receptors. This pharmacological profile makes it a critical active pharmaceutical ingredient (API) for targeted therapeutic applications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in women's healthcare and endocrinology.

Application

• Pharmaceutical API: Primary use as the active ingredient in medications for medical termination of early pregnancy.
• Hormone Research: A vital tool in biochemical and pharmacological studies of progesterone and glucocorticoid receptor pathways.
• Therapeutic Development: Investigated for potential applications in treating Cushing's syndrome, uterine fibroids, endometriosis, and certain hormone-dependent cancers.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Clinical Trial Material: Supplied as a key component for pre-clinical and clinical research studies.

Basic Information

Product Name	Mifepristone
CAS No.	84371-65-3
Molecular Formula	C₂₉H₃₅NO₂
Molecular Weight	429.60 g/mol
Synonyms	RU-486; RU 38486; Mifegyne; Mifeprex; 11β-(4-Dimethylaminophenyl)-17β-hydroxy-17α-(1-propynyl)-estra-4,9-dien-3-one; ZK 98296; Abortione; Lunarette
EINECS	Contact for details

Quality Control

Our Mifepristone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.