Description

(8S,9S,13S,14S)-17-Ethynyl-3-Methoxy-13-Methyl-7,8,9,11,12,14,15,16-Octahydro-6H-Cyclopenta[A]Phenanthrene-2,17-Diol is a high-purity steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is essential for research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of steroidal drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroidal drugs and hormone analogs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.
• Biochemical Research: Tool compound for studying steroid receptor interactions, enzyme inhibition, and metabolic pathways in preclinical research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development and scale-up of new therapeutic agents.
• Academic Research: Utilized in universities and research institutes for chemical synthesis projects and biological activity studies.

Basic Information

Product Name	(8S,9S,13S,14S)-17-Ethynyl-3-Methoxy-13-Methyl-7,8,9,11,12,14,15,16-Octahydro-6H-Cyclopenta[A]Phenanthrene-2,17-Diol
CAS No.	26011-40-5
Molecular Formula	C21H26O3
Molecular Weight	326.43 g/mol
Synonyms	17α-Ethynylestradiol 3-Methyl Ether; 17α-Ethynyl-3-methoxyestra-1,3,5(10)-trien-17β-ol; 3-Methoxy-17α-ethynylestra-1,3,5(10)-trien-17β-ol; EE2 3-Methyl Ether; Ethynylestradiol 3-Methyl Ether; Mestranol Impurity/Intermediate; (8S,9S,13S,14S)-17-Ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2,17-diol
EINECS	Contact for details

Quality Control

Our (8S,9S,13S,14S)-17-Ethynyl-3-Methoxy-13-Methyl-7,8,9,11,12,14,15,16-Octahydro-6H-Cyclopenta[A]Phenanthrene-2,17-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopeial standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.