Description

Ginkgolide B is a highly purified, biologically active terpene lactone isolated from the leaves of the Ginkgo biloba tree. This specific compound is a key marker for the standardization of Ginkgo biloba extracts, valued for its potent and selective platelet-activating factor (PAF) receptor antagonistic activity. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and advanced research sectors for the development of standardized herbal medicines, dietary supplements, and as a critical reference standard in analytical laboratories.

Application

• Pharmaceutical Reference Standard: Serves as a primary chemical reference material (CRM) for the identification, assay, and quality control of Ginkgo biloba extracts and finished products.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the research and development of novel pharmaceutical formulations targeting circulatory disorders, inflammation, and cognitive function.
• Nutraceutical Standardization: Employed to standardize and quantify the active terpene lactone content in high-quality dietary supplements to ensure potency and batch-to-batch consistency.
• Biomedical Research: A critical tool for in vitro and in vivo studies investigating PAF-mediated pathways, neuroprotection, anti-inflammatory mechanisms, and oxidative stress.
• Analytical Chemistry: Essential for method development and validation in laboratories using techniques like HPLC, LC-MS, and TLC for phytochemical analysis.
• Cosmeceutical Research: Investigated for potential applications in topical formulations aimed at improving skin microcirculation and providing antioxidant benefits.

Basic Information

Product Name	Ginkgolide B
CAS No.	99796-69-7
Molecular Formula	C20H24O10
Molecular Weight	424.40 g/mol
Synonyms	BN 52021; Ginkgolide B; (1R,2S,3R,6R,10S,14S)-5,10-Dihydroxy-3,14-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-4,8,16-trione; Ginkgolide-B; Bilobalide B (obsolete); Contact for details on EINECS

Quality Control

Our Ginkgolide B is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to meet exacting standards for research and pharmaceutical applications. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.