Description

1-(4-Trifluoromethylphenyl)-2-Nitroethylene is a versatile nitroethylene derivative characterized by a trifluoromethylphenyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in organic synthesis, enabling the introduction of both nitro and fluorinated aromatic functionalities. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing novel herbicides and pesticides, leveraging the biological activity of the nitroethylene and trifluoromethyl groups.
• Material Science Research: Used in the development of organic semiconductors and non-linear optical (NLO) materials due to its electron-accepting properties.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions for constructing complex molecular architectures.
• Fluorine Chemistry Studies: An important reagent for investigating the effects of fluorine substitution on chemical reactivity and physical properties.
• Academic & Industrial R&D: Essential for method development and discovery chemistry in both university and corporate research laboratories.

Basic Information

Product Name	1-(4-Trifluoromethylphenyl)-2-Nitroethylene
CAS No.	99696-01-2
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	(2E)-1-[4-(Trifluoromethyl)phenyl]-2-nitroethene; (E)-1-(4-Trifluoromethylphenyl)-2-nitroethylene; 4-Trifluoromethyl-β-nitrostyrene; 2-Nitro-1-[4-(trifluoromethyl)phenyl]ethene; α-(4-Trifluoromethylphenyl)-β-nitroethylene; 1-(4-Trifluoromethylphenyl)-2-nitroethene; (E)-4-(Trifluoromethyl)-β-nitrostyrene; p-Trifluoromethyl-β-nitrostyrene
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethylphenyl)-2-Nitroethylene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and GC are provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.