Description

5,5'-Bis-Trifluoromethyl-2,2'-Dichlorobiphenyl is a specialized halogenated biphenyl derivative, distinguished by its unique trifluoromethyl and chloro substituents. This compound serves as a critical high-performance intermediate in advanced organic synthesis, valued for its ability to impart specific electronic and steric properties to target molecules. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the production of specialty materials for electronic displays and optoelectronic devices.
• Polymer & Resin Modifier: Incorporated into high-performance polymers to improve thermal stability, chemical resistance, and specific functional properties.
• Catalyst Ligand Precursor: Utilized in the synthesis of sophisticated ligand systems for transition metal catalysis in fine chemical manufacturing.
• Academic & Industrial R&D: Essential reagent for research in organic chemistry, fluorochemistry, and materials science.

Basic Information

Product Name	5,5'-Bis-Trifluoromethyl-2,2'-Dichlorobiphenyl
CAS No.	99686-52-9
Molecular Formula	C14H6Cl2F6
Molecular Weight	359.10 g/mol
Synonyms	2,2'-Dichloro-5,5'-bis(trifluoromethyl)biphenyl; 2,2'-Dichloro-α,α,α,α',α',α'-hexafluoro-5,5'-dimethylbiphenyl; 5,5'-Bis(trifluoromethyl)-2,2'-dichlorobiphenyl; 2,2'-Dichloro-5,5'-di(trifluoromethyl)-1,1'-biphenyl; 1,1'-Biphenyl, 2,2'-dichloro-5,5'-bis(trifluoromethyl)-; BTFDCB
EINECS	Contact for details

Quality Control

Our production of 5,5'-Bis-Trifluoromethyl-2,2'-Dichlorobiphenyl adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP requirements for use in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.