Description

Diacetylspiramycin Iii is a semi-synthetic derivative of the macrolide antibiotic spiramycin, specifically the acetylated form of its third component. This compound is valued for its enhanced stability and bioavailability compared to its parent molecule, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors for the research, development, and production of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced macrolide antibiotics.
• Antibacterial Research: Used in microbiological and pharmacological research to study structure-activity relationships and mechanisms of action.
• Veterinary Medicine Development: Employed in the formulation of antibacterial treatments for livestock and companion animals.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical testing in regulatory compliance.
• API Synthesis: Critical component in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) targeting Gram-positive bacterial infections.

Basic Information

Product Name	Diacetylspiramycin Iii
CAS No.	99664-83-2
Molecular Formula	C48H82N2O17
Molecular Weight	959.18 g/mol
Synonyms	Diacetylspiramycin III; Spiramycin III Diacetate; Foromacidin D Diacetate; 4''-O-Acetylspiramycin III; (3R,4S,5S,6R,8R,9R,10E,12E,15R)-5-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-9-ethyl-8,15-dihydroxy-3,4,6,8,10,12,15-heptamethyl-1-oxacyclopentadeca-10,12-dien-2-one Diacetate; Antibiotic A 231 Diacetate; Sequamycin Diacetate; Rovamycin Derivative
EINECS	Contact for details

Quality Control

Our Diacetylspiramycin Iii is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements, such as ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.