Description

Toluene-4-Isocyanate-2-Amine is a specialized aromatic amine derivative with an isocyanate functional group, serving as a versatile and reactive chemical intermediate. Its core value lies in enabling the synthesis of complex molecules, particularly in the development of advanced polymers and fine chemicals, where precise structural control is paramount. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and high-performance materials industries seeking to create novel urethane-based compounds, dyes, or pharmaceutical active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a toluenediamine-isocyanate hybrid structure.
• Agrochemical Synthesis: Used in the production of specialized herbicides, fungicides, and pesticides where its aromatic amine and isocyanate functionalities contribute to biological activity.
• Polymer & Resin Production: Serves as a monomer or chain extender in the manufacture of polyurethanes, polyureas, and other specialty polymers, imparting specific mechanical and chemical resistance properties.
• Dye & Pigment Manufacturing: Acts as a precursor in the synthesis of azo dyes and complex organic pigments, contributing to color fastness and stability.
• Crosslinking Agent: Utilized in coatings, adhesives, and sealants formulations to enhance durability, hardness, and chemical resistance through crosslinking reactions.
• Chemical Research & Development: A valuable reagent in organic synthesis for academic and industrial R&D, enabling the exploration of new reaction pathways and molecular architectures.

Basic Information

Product Name	Toluene-4-Isocyanate-2-Amine
CAS No.	99626-88-7
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	2-Amino-4-isocyanatotoluene; 4-Methyl-3-isocyanatoaniline; 3-Amino-6-isocyanatotoluene; 2-Methyl-5-isocyanatoaniline; Toluene-2-amino-4-isocyanate; 4-Isocyanato-2-methylaniline; 2-Methyl-1-amino-4-isocyanatobenzene; TDI Amine Derivative
EINECS	Contact for details

Quality Control

Our Toluene-4-Isocyanate-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized and highly volatile; it must be stored under an inert atmosphere (e.g., nitrogen or argon) and kept away from heat, sparks, and open flames. Keep container tightly sealed when not in use to prevent moisture ingress and volatilization.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.