Description

(-)-B-Methoxydiisopinocampheylborane is a highly valuable, enantiomerically pure organoborane reagent. This compound matters for its exceptional ability to perform highly stereoselective transformations, making it a cornerstone in the synthesis of complex chiral molecules. It is primarily needed by research and development chemists in the pharmaceutical and fine chemical industries for the production of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Synthesis: A key chiral reducing agent for the enantioselective reduction of prochiral ketones to secondary alcohols.
• Pharmaceutical Intermediates: Critical for the synthesis of chiral building blocks used in drug discovery and development.
• Natural Product Synthesis: Employed in the stereocontrolled construction of complex natural products with multiple chiral centers.
• Agrochemical Research: Used to create enantiomerically pure compounds for advanced crop protection agents.
• Material Science: Potential applications in the development of chiral polymers and advanced organic materials.
• Methodology Development: A benchmark reagent for developing new catalytic and stoichiometric asymmetric methodologies in academic and industrial labs.

Basic Information

Product Name	(-)-B-Methoxydiisopinocampheylborane
CAS No.	99438-28-5
Molecular Formula	C21H37BO
Molecular Weight	316.33 g/mol
Synonyms	(-)-B-Methoxybis(3-pinanyl)borane; (-)-Diisopinocampheylmethoxyborane; (-)-Methoxydiisopinocampheylborane; (1R)-(-)-B-Methoxydiisopinocampheylborane; (1R,2S,5R)-(-)-B-Methoxydiisopinocampheylborane; Alpine-Borane® (related reagent class); DIP-Chloride® analogue (methoxy variant)
EINECS	Contact for details

Quality Control

Our (-)-B-Methoxydiisopinocampheylborane is produced under stringent quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques, including NMR and chiral HPLC, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is moisture-sensitive and easily oxidized; prolonged exposure to air or moisture must be avoided to maintain reagent integrity.

Specification

Item	Specification
Appearance	White to off-white solid or solution
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (ee)	≥ 98.0%
Assay (Titration)	Contact for details
Solvent (if supplied as solution)	Specified (e.g., Tetrahydrofuran, Hexanes)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.