Description

n-Acetylboromycin is a semi-synthetic derivative of the naturally occurring polyketide antibiotic boromycin, distinguished by the acetylation of a key hydroxyl group. This modification is strategically employed to enhance the compound's pharmacological profile, potentially improving its stability, bioavailability, or target specificity for advanced research applications. It serves as a critical intermediate and reference standard for pharmaceutical R&D teams and academic institutions focused on developing novel anti-infective agents and studying ionophore mechanisms. The compound, identified by CAS NO 99292-90-7, is supplied under stringent quality controls to ensure reliability for sensitive experimental work.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis and structure-activity relationship (SAR) studies of next-generation antibiotic candidates.
• Reference Standard for Analytical Testing: Used as a high-purity calibrant in HPLC, LC-MS, and NMR methods for quality control and method development in API manufacturing.
• Mechanistic Studies in Microbiology: Employed in biochemical research to investigate the mode of action of ionophore antibiotics against Gram-positive bacteria and other pathogens.
• Chemical Biology Probes: Utilized to study potassium ion transport across cell membranes and its role in cellular processes.
• Academic & Institutional Research: A vital tool for universities and research institutes exploring novel polyketide-derived therapeutics.

Basic Information

Product Name	n-Acetylboromycin
CAS No.	99292-90-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Acetylboromycin; Boromycin acetate derivative; Antibiotic X 5108 acetate; (2R,3S,4S,5S,6R)-5-[(3S,5S,7S,9R,10S,12R,13S,14E,16E,18R,19R,20R,21S,23S,24R,26S,27R,28S,29S)-28-Acetyloxy-23-ethyl-5,7,9,19,21,24,27-heptahydroxy-3,10,12,14,16,20,26,29-octamethyl-2,6,8,11,13,15,17,22,25-nonaoxaoctacyclo[13.12.1.1³,¹⁰.0⁴,⁹.0¹²,²⁰.0¹³,¹⁸.0²¹,²⁹.0²⁴,²⁸]nonacosan-30-yl]oxy-6-methyloxane-2,3,4-triol (IUPAC);
EINECS	Contact for details

Quality Control

Our n-Acetylboromycin is manufactured and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and identity. We support compliance with various research and development protocols, ensuring traceability and consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.