Description

Saquayamycin B is a potent ansamycin-class antibiotic compound with significant biological activity. This specialized chemical is valued in research and development for its unique mechanism of action and potential as a lead compound. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and academic institutions engaged in antimicrobial and anticancer drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of novel antibiotics and chemotherapeutic agents.
• Antimicrobial Studies: Used in microbiological research to study its mechanism of action against Gram-positive bacteria and other resistant pathogens.
• Oncology Research: Investigated for its cytotoxic properties and potential application in developing targeted cancer therapies.
• Biochemical Pathway Analysis: Employed as a tool compound to inhibit specific enzymatic processes and elucidate biological pathways.
• High-Throughput Screening (HTS): Utilized in compound libraries for screening campaigns to identify new drug candidates with similar scaffolds.

Basic Information

Product Name	Saquayamycin B
CAS No.	99260-67-0
Molecular Formula	C39H48N2O12
Molecular Weight	736.81 g/mol
Synonyms	Saquayamycin B; Antibiotic BMY-28438; BMY 28438; BMY-28438; 5,12-Dideoxy-6-O-methyl-12-oxo-6a,12a-didehydro-6H,12H-naphtho[1,2-b:5,6-b']dipyran-2-carboxylic acid, 7-[(6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-α-L-mannopyranosyl)oxy]-1,3,4,10,11-pentahydroxy-9-methoxy-8,13-dimethyl-11-oxo-, (6aR,12aS)-; Naphthomycin G
EINECS	Contact for details

Quality Control

Our Saquayamycin B is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and microbiological assay for potency. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment to ensure compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. The container should be kept in a dry, well-ventilated area and allowed to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 1.0%
Potency (Microbiological Assay)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.