Description

Pristimerin is a naturally occurring quinonoid triterpenoid compound, recognized for its potent biological activities. This high-purity compound is critical for research and development in life sciences, offering a reliable reference standard and active ingredient. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions focused on oncology, inflammation, and metabolic disease studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in drug discovery programs targeting cancer, inflammation, and infectious diseases.
• Biochemical & Cell Biology Studies: Used as a potent inhibitor to investigate cellular signaling pathways, particularly those involving NF-κB and STAT3, for mechanistic research.
• Academic & Preclinical Research: Employed in university and institutional labs for in vitro and in vivo studies to validate therapeutic hypotheses and explore new treatment modalities.
• Natural Product Standardization: Acts as a certified reference material for the quality control and standardization of herbal extracts and nutraceutical products containing *Celastrus* or *Maytenus* species.
• High-Throughput Screening (HTS): Utilized in compound libraries for screening campaigns to identify novel drug candidates with specific biological targets.

Basic Information

Product Name	Pristimerin
CAS No.	1258-84-0
Molecular Formula	C30H40O4
Molecular Weight	464.64 g/mol
Synonyms	Pristimerin; NSC 167780; 20α-3-Hydroxy-2-oxo-24-nor-friedela-1,3,5,7-tetraen-29-oic acid δ-lactone; Celastrol derivative; (20α)-3-Hydroxy-2-oxo-24-nor-1,3,5,7-friedelatetraen-29-oic acid, δ-lactone
EINECS	Contact for details

Quality Control

Our Pristimerin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.