Description

8-Azabicyclo[3.2.1]Oct-2-Ene-2-Carboxaldehyde, 8-Methyl-, (1R,5S)- (9Ci) is a high-purity, stereochemically defined bicyclic organic compound that serves as a critical chiral building block in advanced synthetic chemistry. Its rigid, nitrogen-containing framework makes it a valuable intermediate for constructing complex molecular architectures with high precision. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific pesticides and herbicides where the defined spatial orientation is crucial for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in enantioselective catalytic reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and medicinal chemistry research programs.
• Material Science: Potential precursor for nitrogen-doped carbon frameworks or advanced polymers with specific structural properties.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Oct-2-Ene-2-Carboxaldehyde, 8-Methyl-, (1R,5S)- (9Ci)
CAS No.	99213-86-2
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(1R,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxaldehyde; 8-Methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carbaldehyde, (1R,5S)-; Tropane-2-carboxaldehyde, 8-methyl-, (1R,5S)-; (1R,5S)-Trop-2-ene-2-carbaldehyde; 8-Methylnortrop-2-ene-2-carboxaldehyde; Endo-8-Methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carbaldehyde; Chiral Tropene Aldehyde; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Oct-2-Ene-2-Carboxaldehyde, 8-Methyl-, (1R,5S)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with relevant ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (1R,5S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.