Description

Rac 6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Methanol is a versatile chiral building block and fluorinated intermediate of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine and the chroman scaffold, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental persistence.
• Chiral Resolution Studies: The racemic mixture (Rac) is used as a starting material for developing and optimizing enantiomeric separation processes.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialized fluorinated polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Rac 6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Methanol
CAS No.	99199-62-9
Molecular Formula	C10H11FO2
Molecular Weight	182.19 g/mol
Synonyms	(±)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol; 6-Fluoro-2-hydroxymethylchroman; 2-(Hydroxymethyl)-6-fluorochroman; 6-Fluorochroman-2-methanol; rac-6-Fluorochroman-2-ylmethanol; 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-; 6-Fluoro-3,4-dihydro-2H-chromen-2-ylmethanol
EINECS	Contact for details

Quality Control

Our production of Rac 6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Methanol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity (HPLC)	Racemic mixture

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.