Description

(+)-(3R,4R)-Bis(Diphenylphosphino)-1-Benzylpyrrolidine(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is a high-purity, chiral rhodium complex widely recognized as an efficient and selective catalyst for asymmetric hydrogenation and other transition metal-catalyzed reactions. Its value lies in enabling the production of enantiomerically pure intermediates critical for pharmaceuticals and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance chiral catalysts.

Application

• Asymmetric Hydrogenation Catalyst: Key for the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Production of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity, such as chiral amines and amino acid derivatives.
• Fine Chemical Synthesis: Enabling complex, stereocontrolled transformations in the synthesis of specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable tool for developing new catalytic methodologies and exploring novel reaction pathways in organic chemistry.
• Agrochemical Intermediate Production: Synthesis of chiral compounds used in the development of advanced herbicides and pesticides.

Basic Information

Product Name	(+)-(3R,4R)-Bis(Diphenylphosphino)-1-Benzylpyrrolidine(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate
CAS No.	99143-48-3
Molecular Formula	C43H43BF4NP2Rh
Molecular Weight	809.47 g/mol
Synonyms	(R,R)-1-Benzyl-3,4-bis(diphenylphosphino)pyrrolidine(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (R,R)-Me-DuPhos(COD)RhBF4; Rhodium(I)-(R,R)-1-Benzyl-2,5-bis(diphenylphosphino)pyrrolidine (1,5-cyclooctadiene) tetrafluoroborate; (R,R)-Bn-PyrPhos(COD)RhBF4; (3R,4R)-1-Benzyl-3,4-bis(diphenylphosphino)pyrrolidine(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (+)-[Rh((R,R)-Bn-PyrPhos)(COD)]BF4; Chiral Rhodium(I) DuPhos Complex
EINECS	Contact for details

Quality Control

Our high-value catalyst is manufactured under strict quality control protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by NMR, HPLC, and elemental analysis to confirm identity, purity, and the absence of deleterious impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light will degrade its catalytic activity.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Rhodium Content	12.5 - 13.0 %
Specific Rotation [α]D20	+150° to +170° (c=0.1 in CH2Cl2)
Solubility	Soluble in dichloromethane, chloroform; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.