Description

(2R,3S)-3-(tert-Butoxycarbonyl)Amino-1,2-Epoxy-4-Phenylbutane is a high-purity chiral epoxide building block of significant importance in asymmetric synthesis. Its primary value lies in serving as a key intermediate for the production of complex pharmaceutical actives, particularly HIV protease inhibitors. This compound is essential for research and development chemists and production teams in the pharmaceutical and fine chemical industries who require enantiomerically pure intermediates for advanced drug synthesis. The CAS number for this compound is 98760-08-8.

Application

• Pharmaceutical Intermediate: Critical chiral synthon in the synthesis of HIV protease inhibitors and other antiviral medications.
• Asymmetric Synthesis: Used as a building block for introducing specific stereochemistry in complex organic molecules.
• Peptidomimetic Research: Serves as a core structure in the development of peptide-like drug candidates.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals and active pharmaceutical ingredients (APIs).
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Used in university and institutional labs for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	(2R,3S)-3-(tert-Butoxycarbonyl)Amino-1,2-Epoxy-4-Phenylbutane
CAS No.	98760-08-8
Molecular Formula	C15H21NO3
Molecular Weight	263.33 g/mol
Synonyms	(2R,3S)-1,2-Epoxy-3-[(tert-butoxycarbonyl)amino]-4-phenylbutane; (2R,3S)-3-[(tert-Butoxycarbonyl)amino]-1,2-epoxy-4-phenylbutane; (2R,3S)-N-Boc-3-amino-1,2-epoxy-4-phenylbutane; N-Boc-(2R,3S)-3-amino-1,2-epoxy-4-phenylbutane; (2R,3S)-3-(Boc-amino)-1,2-epoxy-4-phenylbutane; Boc-Aminoepoxyphenylbutane; Epoxy Boc-phenylalanine derivative
EINECS	Contact for details

Quality Control

Our (2R,3S)-3-(tert-Butoxycarbonyl)Amino-1,2-Epoxy-4-Phenylbutane is manufactured under strict quality control protocols suitable for pharmaceutical intermediate applications. Products undergo rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each batch to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.