Description

4-Adamantyl-1-Iodobenzene is a high-value, functionalized aromatic building block featuring the rigid adamantyl group and a reactive iodine substituent. This compound is essential for advanced organic synthesis, offering a unique combination of steric bulk and versatile reactivity for constructing complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions, ligand synthesis, and the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, via Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the adamantyl moiety can enhance biological activity and environmental stability.
• Material Science: Acts as a monomer or building block for creating advanced polymers, liquid crystals, and organic semiconductors with tailored thermal and electronic properties.
• Catalyst & Ligand Development: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes due to its potential for further functionalization.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry, exploring new C-C and C-heteroatom bond-forming reactions.

Basic Information

Product Name	4-Adamantyl-1-Iodobenzene
CAS No.	98611-00-8
Molecular Formula	C16H19I
Molecular Weight	338.23 g/mol
Synonyms	1-(4-Iodophenyl)adamantane; 4-Iodophenyladamantane; p-Iodophenyladamantane; Adamantyl-4-iodobenzene; (4-Iodophenyl)tricyclo[3.3.1.13,7]decane; 4-(1-Adamantyl)iodobenzene; 98611-00-8
EINECS	Contact for details

Quality Control

Every batch of 4-Adamantyl-1-Iodobenzene is manufactured and tested under strict quality management protocols to ensure consistency and high purity for research and development applications. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.