Description

4-Bromo-2-Chloro-5-Methoxyaniline is a halogenated aniline derivative that serves as a crucial building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor antagonists, and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where its halogenated structure contributes to product efficacy and stability.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other high-performance colorants, offering excellent lightfastness and color properties.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers due to its electron-donating methoxy and electron-withdrawing halogen groups.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination or Suzuki-Miyaura coupling for C-N and C-C bond formation.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	4-Bromo-2-Chloro-5-Methoxyaniline
CAS No.	98446-54-9
Molecular Formula	C7H7BrClNO
Molecular Weight	236.49 g/mol
Synonyms	2-Chloro-4-bromo-5-methoxyaniline; 5-Methoxy-2-chloro-4-bromoaniline; Benzenamine, 4-bromo-2-chloro-5-methoxy-; 4-Bromo-2-chloro-5-methoxybenzenamine; 2-Chloro-4-bromo-5-methoxy-phenylamine; 98446-54-9; 4-Br-2-Cl-5-MeO-aniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-5-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.