Description

3-(1-Adamantyl)-2-Bromopropanoic Acid is a specialized brominated adamantane derivative that serves as a high-value synthetic intermediate. This compound is prized for its unique adamantyl cage structure, which imparts significant steric bulk and lipophilicity, making it a critical building block in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, viral infections, and metabolic diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the adamantyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent for creating advanced polymers with unique thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions to introduce the sterically demanding adamantyl moiety.
• Ligand and Catalyst Development: Useful for constructing complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study enzyme function and protein-protein interactions.

Basic Information

Product Name	3-(1-Adamantyl)-2-Bromopropanoic Acid
CAS No.	98398-67-5
Molecular Formula	C₁₃H₁₉BrO₂
Molecular Weight	287.20 g/mol
Synonyms	2-Bromo-3-(1-adamantyl)propanoic Acid; 3-(Adamantan-1-yl)-2-bromopropanoic Acid; 2-Bromo-3-tricyclo[3.3.1.1³,⁷]dec-1-ylpropanoic Acid; 1-Adamantyl-2-bromopropionic Acid; NSC 405124; Adamantyl Bromopropionic Acid; Bromoadamantylpropanoic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-(1-Adamantyl)-2-Bromopropanoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its sensitivity, the container should be kept tightly sealed under an inert atmosphere when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.