Description

Brevetoxin (9Ci) is a potent marine neurotoxin belonging to the class of polycyclic ether compounds, primarily produced by the dinoflagellate *Karenia brevis*. This compound is of significant interest for its specific mechanism of action as a voltage-gated sodium channel activator. It serves as a critical reference standard and research tool for scientists in toxicology, pharmacology, and environmental monitoring, enabling the study of harmful algal blooms (red tides), seafood safety, and neurophysiological pathways.

Application

• Marine Toxin Research: Primary reference material for studying the biochemistry and toxicology of brevetoxins.
• Environmental Monitoring: Calibration standard for analytical methods (e.g., LC-MS, ELISA) to detect and quantify brevetoxins in seawater and shellfish.
• Pharmacological Studies: Tool compound for investigating voltage-gated sodium channel function and neurotoxicity mechanisms.
• Seafood Safety & Regulatory Compliance: Used to validate testing protocols for monitoring brevetoxin contamination in commercial shellfish to ensure public health safety.
• Antibody & Assay Development: Critical for the production and calibration of antibodies used in diagnostic test kits for brevetoxin detection.
• Academic & Institutional Research: Fundamental compound for universities and government agencies conducting studies on harmful algal blooms (HABs) and their ecological impact.

Basic Information

Product Name	Brevetoxin (9Ci)
CAS No.	98225-48-0
Molecular Formula	C50H70O13
Molecular Weight	879.1 g/mol
Synonyms	Brevetoxin-9; PbTx-9; Brevetoxin B5; GB-5; 42,43,44,47,48,49,50,51,52,53-Decahydro-34,41:36,39-diepoxy-38-hydroxy-4,6,10,14,18,22,26,30,34-nonaoxa-3,5,9,13,17,21,25,29,33-nonamethyldotetracontane-2,46-dione; (2S,3aS,4R,5S,6S,7R,8S,9R,10S,11R,12S,13R,14S,15R,16S,17R,18S,19R,20S,21R,22S,23R,24S,25R,26S,27R,28S,29R,30S,31R,32S,33R,34S,35R,36S,37R,38S,39R,40S,41R,42S,43R,44S,45R,46S,47R,48S,49R,50S)-Isomer
EINECS	Contact for details

Quality Control

Our Brevetoxin (9Ci) is produced and handled under strict quality protocols to ensure identity, purity, and stability for critical research applications. Each batch is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identification, and chromatographic data is provided to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. For long-term storage, consider storage under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to reference
Purity (HPLC)	≥ 95% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in methanol, ethanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.