Description

Nivalenol Tetraacetate is a key acetylated derivative of the trichothecene mycotoxin nivalenol. This compound is of significant importance in analytical chemistry and toxicology research, serving as a crucial reference standard and precursor for method development. It is primarily utilized by research institutions, diagnostic laboratories, and agrochemical companies involved in mycotoxin analysis, food safety testing, and the study of fungal metabolites.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the accurate quantification of nivalenol and its derivatives via HPLC, LC-MS/MS, or GC-MS.
• Food Safety & Toxicology Research: Essential for developing and validating analytical methods to detect and measure nivalenol contamination in grains, cereals, and food products.
• Metabolite Studies: Used in research to study the metabolism, biotransformation, and environmental fate of trichothecene mycotoxins.
• Diagnostic Kit Development: Acts as a critical antigen or hapten in the production of antibodies for immunoassay-based detection kits (e.g., ELISA).
• Pharmaceutical Research: Employed in biochemical research to investigate the mechanisms of trichothecene toxicity and potential inhibitory effects.
• Quality Control Laboratories: Used for system suitability testing, calibrating equipment, and ensuring the accuracy of mycotoxin testing protocols in commercial labs.

Basic Information

Product Name	Nivalenol Tetraacetate
CAS No.	14287-83-3
Molecular Formula	C21H28O10
Molecular Weight	440.44 g/mol
Synonyms	4β,15-Diacetoxy-3α,7α-dihydroxy-12,13-epoxytrichothec-9-en-8-one; 3α,4β,7α,15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one tetraacetate; NIV Tetraacetate; 8-Oxo-12,13-epoxytrichothec-9-ene-3,4,7,15-tetrol tetraacetate; Nivalenol 3,4,7,15-Tetraacetate; 3,4,7,15-Tetra-O-acetylnivalenol
EINECS	Contact for details

Quality Control

Our Nivalenol Tetraacetate is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR) and purity assessment by chromatographic techniques (HPLC). We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on purity, related substances, and residual solvents. Our quality commitment ensures the material is suitable for its intended use as a high-grade analytical standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.