Description

[1R,(-)]-2-Formyl-1,4,4Aα,5,6,7,8,8A-Octahydro-5,5,8Aβ-Trimethyl-1β-Naphthalenecarboxylic Acid is a high-purity, chiral synthetic intermediate with a complex decalin-based structure. This compound matters as a critical building block for the synthesis of advanced pharmaceutical agents and fine chemicals, where its defined stereochemistry is essential for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic compounds and high-value chemical products.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of retinoid analogs, vitamin A derivatives, and other bioactive molecules.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including Diels-Alder reactions and carbonyl chemistry, to construct intricate polycyclic frameworks.
• Research & Development (R&D): Serves as a standard or starting material in medicinal chemistry programs for drug discovery and process development.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high stereochemical purity.
• Agrochemical Synthesis: Potential intermediate in creating novel pesticides or plant growth regulators with specific stereoisomeric activity.

Basic Information

Product Name	[1R,(-)]-2-Formyl-1,4,4Aα,5,6,7,8,8A-Octahydro-5,5,8Aβ-Trimethyl-1β-Naphthalenecarboxylic Acid
CAS No.	98204-84-3
Molecular Formula	C₁₅H₂₂O₃
Molecular Weight	250.33 g/mol
Synonyms	(1R)-2-Formyl-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1-naphthalenecarboxylic acid; (-)-2-Formyl-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1-naphthalenecarboxylic acid; (1R)-2-Formyl-5,5,8a-trimethyl-1,2,3,4,4a,5,6,7,8,8a-decahydro-1-naphthalenecarboxylic acid; 1R-(-)-2-Formyl-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1-naphthoic Acid; (1R)-5,5,8a-Trimethyl-2-formyl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our [1R,(-)]-2-Formyl-1,4,4Aα,5,6,7,8,8A-Octahydro-5,5,8Aβ-Trimethyl-1β-Naphthalenecarboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.