Description

tert-Butyl [(1S)-2-Cyclohexyl-1-Formylethyl]Carbamate is a high-value chiral building block and protected amino aldehyde derivative essential for advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex, stereochemically defined molecules, particularly in pharmaceutical research and development. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the asymmetric synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Peptidomimetics & Protease Inhibitor Synthesis: Serves as a key building block for creating peptide analogs and inhibitors of enzymes like proteases, which are important targets in antiviral and anticancer therapies.
• Agrochemical Active Ingredient Development: Used in the research and scale-up of chiral pesticides and herbicides, where specific stereochemistry is required for optimal activity and environmental safety.
• Asymmetric Catalysis & Ligand Synthesis: Employed in the preparation of chiral ligands and catalysts used in enantioselective transformations to produce other high-value intermediates.
• Custom Synthesis & Contract Manufacturing: A requested material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific projects requiring advanced chiral aldehydes.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in organic methodology development and the exploration of new chemical spaces.

Basic Information

Product Name	tert-Butyl [(1S)-2-Cyclohexyl-1-Formylethyl]Carbamate
CAS No.	98105-42-1
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclohexylpropanal; Boc-L-cyclohexylalaninal; N-Boc-L-cyclohexylalaninal; (S)-N-(tert-Butoxycarbonyl)-3-cyclohexylalaninal; tert-Butyl N-[(1S)-2-cyclohexyl-1-formylethyl]carbamate; (S)-2-(Boc-amino)-3-cyclohexylpropionaldehyde; Boc-Cyh-Ala-H; (S)-3-Cyclohexyl-2-((tert-butoxycarbonyl)amino)propanal
EINECS	Contact for details

Quality Control

Our tert-Butyl [(1S)-2-Cyclohexyl-1-Formylethyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, the container should be kept tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white solid or colorless to pale yellow oil/liquid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.