Description

3-(Difluoromethoxy)-4-Methoxyaniline is a specialized aromatic amine derivative featuring both difluoromethoxy and methoxy substituents, making it a valuable fluorinated building block in advanced synthesis. This compound is critical for introducing specific fluorine-containing motifs into target molecules, which can dramatically alter their physical, chemical, and biological properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated aromatic systems that can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluoromethoxy group can enhance biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Functional Polymer Monomer: Employed to create specialty polymers with unique surface properties, chemical resistance, or specific optical characteristics.
• Organic Synthesis Building Block: Utilized in academic and industrial research laboratories for constructing complex fluorinated molecules for various material science and life science applications.

Basic Information

Product Name	3-(Difluoromethoxy)-4-Methoxyaniline
CAS No.	97963-82-1
Molecular Formula	C8H9F2NO2
Molecular Weight	189.16 g/mol
Synonyms	4-Methoxy-3-(difluoromethoxy)aniline; 3-(Difluoromethoxy)-p-anisidine; 4-Amino-2-(difluoromethoxy)anisole; Benzenamine, 3-(difluoromethoxy)-4-methoxy-; 97963-82-1; 3-Difluoromethoxy-4-methoxyaniline; 4-Methoxy-3-difluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our production of 3-(Difluoromethoxy)-4-Methoxyaniline adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We are committed to meeting the exacting requirements of our clients in regulated industries, and specifications can be aligned with cGMP or other relevant quality frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine nature and light-sensitive properties, prolonged exposure to air and light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.