Description

trans-2-Amino-4-Cyclohexene-1-Carboxylic Acid is a specialized chiral amino acid derivative featuring a cyclohexene ring, making it a valuable non-proteinogenic building block for advanced organic synthesis. This compound is particularly significant for its rigid, unsaturated cyclic structure, which is instrumental in constructing conformationally constrained peptide mimetics and bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly protease inhibitors and receptor antagonists.
• Peptidomimetics Research: Used to introduce conformational constraints into peptide backbones, enhancing metabolic stability and biological activity.
• Medicinal Chemistry: Serves as a building block for creating focused libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in studies investigating enzyme-substrate interactions and the role of specific amino acid conformations.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to generate enantiomerically pure compounds.

Basic Information

Product Name	trans-2-Amino-4-Cyclohexene-1-Carboxylic Acid
CAS No.	97945-19-2
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	(1R,2S,4S)-2-Amino-4-cyclohexene-1-carboxylic acid; (1R,2S,4S)-2-Amino-4-cyclohexenecarboxylic acid; trans-2-Amino-4-cyclohexene-1-carboxylic acid; 2-Amino-4-cyclohexene-1-carboxylic acid; 4-Cyclohexene-1-carboxylic acid, 2-amino-, (1R,2S,4S)-rel-; Cyclohex-4-ene-1-carboxylic acid, 2-amino-, (1R,2S,4S)-
EINECS	Contact for details

Quality Control

Our trans-2-Amino-4-Cyclohexene-1-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.