Description

2-Deoxy-2-Fluoro-1,3,5-Tri-o-Benzoyl-D-Ribofuranose is a key fluorinated ribofuranose derivative, serving as a critical protected intermediate in nucleoside synthesis. Its primary value lies in enabling the efficient and selective introduction of fluorine into sugar moieties, a modification essential for developing novel antiviral and anticancer therapeutics. This high-purity building block is indispensable for pharmaceutical R&D and process chemistry teams focused on creating next-generation nucleoside analogs.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of fluorinated nucleoside analogs, including antiviral and anticancer agents.
• Antiviral Drug Development: Used in the research and production of fluorinated nucleosides targeting viruses such as hepatitis and influenza.
• Anticancer Agent Synthesis: Employed as a building block for creating fluoropyrimidine and other fluoronucleoside-based chemotherapeutics.
• Proteomics & Biochemistry Research: Acts as a tool compound for studying enzyme mechanisms and metabolic pathways involving fluorinated sugars.
• Process Chemistry & Scale-up: Serves as a reliable, high-quality intermediate for optimizing and scaling manufacturing routes for active pharmaceutical ingredients (APIs).
• Radiopharmaceutical Precursor: Potential use in the synthesis of F-18 labeled compounds for Positron Emission Tomography (PET) imaging agents.

Basic Information

Product Name	2-Deoxy-2-Fluoro-1,3,5-Tri-o-Benzoyl-D-Ribofuranose
CAS No.	97614-43-2
Molecular Formula	C26H21FO7
Molecular Weight	464.44 g/mol
Synonyms	1,3,5-Tri-O-benzoyl-2-deoxy-2-fluoro-D-ribofuranose; 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α/β-D-ribofuranose; 2-Fluoro-2-deoxy-1,3,5-tri-O-benzoyl-D-ribofuranose; 2-Fluoro-1,3,5-tri-O-benzoyl-2-deoxy-D-ribofuranose; 2-Fluoro-2-deoxy-1,3,5-tri-O-benzoyl-α-D-ribofuranose; 2'-Deoxy-2'-fluoro-1,3,5-tri-O-benzoyl-D-ribofuranose; 2-F-1,3,5-TriBz-D-Ribofuranose
EINECS	Contact for details

Quality Control

Our 2-Deoxy-2-Fluoro-1,3,5-Tri-o-Benzoyl-D-Ribofuranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with full batch traceability are provided.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.