Description

3-Methyl-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Butan-1-Amine is a valuable, protected amine boronic ester derivative, serving as a versatile building block in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions and functional group transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific amine-boronate functionalities.
• Organic Ligand Precursor: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Polymer & Material Science: Incorporated into specialty polymers and organic frameworks to modify physical and chemical properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and bioconjugation reagents due to its reactive handles.
• Academic & Process R&D: A critical reagent for method development and exploring new synthetic routes in research laboratories.

Basic Information

Product Name	3-Methyl-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Butan-1-Amine
CAS No.	97532-80-4
Molecular Formula	C11H24BNO2
Molecular Weight	213.13 g/mol
Synonyms	1-Amino-3-methylbutylboronic acid pinacol ester; 3-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butan-1-amine; (1-Amino-3-methylbutyl)boronic acid pinacol ester; 3-Methyl-1-(pinacolatoboryl)butan-1-amine; 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylbutan-1-amine; Isoamylamine MIDA boronate (protected form); B-(1-Amino-3-methylbutyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Butan-1-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for critical applications. All materials are subjected to rigorous analytical testing, including NMR, HPLC, and GC analysis. Certificates of Analysis (COA) detailing purity and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.