Description

N,n-Diethyl-2,3,3-Trifluoroacrylamide is a specialized fluorinated acrylamide derivative, a key building block in advanced organic synthesis. Its unique trifluoroacrylamide structure makes it a valuable precursor for introducing fluorine-containing motifs into target molecules, which is critical for modulating the physical, chemical, and biological properties of final products. This compound is essential for research and development in the pharmaceutical, agrochemical, and advanced materials sectors, where fluorination strategies are employed to enhance metabolic stability, bioavailability, and material performance.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in creating fluorinated analogs to improve drug potency and pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where fluorine atoms contribute to enhanced efficacy and environmental persistence.
• Functional Material Precursor: A key monomer or intermediate in the synthesis of specialty polymers, coatings, and liquid crystals that require specific fluorochemical properties for thermal stability, chemical resistance, or surface activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules via reactions like Michael additions, cyclizations, and cross-coupling, leveraging its reactive acrylamide double bond.
• Fluorine Chemistry Research: A valuable reagent for studying new fluorination methodologies and the effects of fluorine substitution on molecular conformation and reactivity.

Basic Information

Item	Details
Product Name	N,n-Diethyl-2,3,3-Trifluoroacrylamide
CAS No.	97403-94-6
Molecular Formula	C7H10F3NO
Molecular Weight	181.16 g/mol
Synonyms	2,3,3-Trifluoro-N,N-diethylacrylamide; N,N-Diethyl-2,3,3-trifluoro-2-propenamide; 2,3,3-Trifluoroacrylic Acid Diethylamide; Diethyl(2,3,3-trifluoroacryl)amide; 97403-94-6; N,N-Diethyl-2,3,3-trifluoroacrylamide
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-2,3,3-Trifluoroacrylamide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.