Description

3Alpha-Hydroxytanshinone Iia is a bioactive diterpenoid quinone compound, a key derivative of the natural product Tanshinone IIA. This compound matters for its significant role as a high-purity reference standard and a crucial intermediate in pharmaceutical research and development. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries focusing on cardiovascular, anti-inflammatory, and anticancer therapeutic areas.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and quantification of Tanshinone-related products in pharmacopoeial analysis.
• Biochemical Research: Serves as a key intermediate or active pharmaceutical ingredient (API) in preclinical studies investigating mechanisms of action for cardiovascular and inflammatory diseases.
• Natural Product Synthesis: Acts as a critical intermediate in the semi-synthesis or structural modification of other bioactive Tanshinone derivatives.
• Nutraceutical Development: Employed in the formulation and standardization of high-end herbal supplements targeting heart health and circulation.
• Academic Research: Utilized in university and institutional labs for pharmacological, metabolic, and pharmacokinetic studies.
• Cosmeceutical Applications: Investigated for potential use in topical formulations aimed at anti-aging and anti-inflammatory skin benefits due to its antioxidant properties.

Basic Information

Product Name	3Alpha-Hydroxytanshinone Iia
CAS No.	97399-71-8
Molecular Formula	C₁₉H₁₈O₅
Molecular Weight	326.34 g/mol
Synonyms	3α-Hydroxytanshinone IIA; 3α-Hydroxy-15,16-dinortanshinone IIA; (3α)-3-Hydroxytanshinone IIA; 3-Hydroxytanshinone IIA (3α-isomer); Tanshinone IIA 3α-ol; 1,6-Dimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-6,10,11-trione, 3-hydroxy-; 3α-Hydroxy-1,6-dimethyl-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-6,10,11-trione
EINECS	Contact for details

Quality Control

Our 3Alpha-Hydroxytanshinone Iia is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.