Description

2,2,3,4,4-Pentafluoro-3-buten-1-ol is a high-value fluorinated alcohol building block, characterized by its unique pentafluoroalkene moiety. This compound is critical for introducing fluorine atoms into target molecules, thereby enhancing their chemical stability, lipophilicity, and biological activity. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for developing fluorinated drug candidates, including protease inhibitors and kinase inhibitors, where fluorine substitution improves metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorinated structure contributes to enhanced efficacy and environmental persistence.
• Fluorinated Polymer Monomer: Serves as a precursor for specialty polymers with unique surface properties, chemical resistance, and low dielectric constants for electronics and coatings.
• Liquid Crystal & OLED Materials: Incorporated into the molecular design of fluorinated liquid crystals and organic light-emitting diode (OLED) materials to optimize performance and stability.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions and nucleophilic additions to create complex fluoroorganic molecules for research and development.
• Surface Active Agent Precursor: Acts as an intermediate for synthesizing fluorinated surfactants and surface modifiers with exceptional wetting and leveling properties.

Basic Information

Product Name	2,2,3,4,4-Pentafluoro-3-buten-1-ol
CAS No.	97168-10-0
Molecular Formula	C4H3F5O
Molecular Weight	162.06 g/mol
Synonyms	3-Buten-1-ol, 2,2,3,4,4-pentafluoro-; Pentafluorobut-3-en-1-ol; 2,2,3,4,4-Pentafluorobut-3-en-1-ol; 4,4,5,5,5-Pentafluoropent-2-en-1-ol (tautomer); 1-Hydroxy-2,2,3,4,4-pentafluorobut-3-ene; Pentafluorovinylmethanol; PFBE-OH; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,2,3,4,4-Pentafluoro-3-buten-1-ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with REACH and other relevant global regulatory frameworks for chemical substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and incompatible with strong bases and fluorides; keep away from such materials. For long-term storage, consider using an inert atmosphere to preserve purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Refractive Index (n20/D)	1.3500 - 1.3600
Density (20°C)	1.500 - 1.600 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.