Description

(1S,6R)-1,3,3,6-Tetramethyl-2,3,5,6-Tetrahydro-1H-Indene-1,7-Dicarbaldehyde is a high-purity, chiral aldehyde derivative of the tetrahydroindene class, serving as a critical advanced intermediate in fine chemical synthesis. Its value lies in its defined stereochemistry and bifunctional aldehyde groups, which enable precise and complex molecular construction. This compound is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and fragrance industries seeking to develop novel active ingredients and specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its complex, functionalized structure.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthetic musks and other complex aroma chemicals due to its tetrahydroindene backbone.
• Material Science Research: Investigated as a monomer or cross-linking agent for the development of specialty polymers with unique thermal or optical properties.
• Asymmetric Catalysis Ligand Precursor: Its chiral framework makes it a valuable starting material for synthesizing novel ligands used in asymmetric hydrogenation and other catalytic processes.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including new C-C bond formation and cyclization reactions.

Basic Information

Item	Detail
Product Name	(1S,6R)-1,3,3,6-Tetramethyl-2,3,5,6-Tetrahydro-1H-Indene-1,7-Dicarbaldehyde
CAS No.	97165-23-6
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	(1S,6R)-1,3,3,6-Tetramethyl-1,2,3,5,6,7-hexahydroinden-1,7-dicarbaldehyde; (1S,6R)-1,3,3,6-Tetramethyl-2,3,5,6-tetrahydro-1H-indene-1,7-dicarboxaldehyde; (-)-Ambrox; 7,8-Dihydro-γ-ionone-7-carboxaldehyde (related derivative); Chiral Tetrahydroindene Dialdehyde; (1S-cis)-1,3,3,6-Tetramethyl-2,3,5,6-tetrahydro-1H-indene-1,7-dicarbaldehyde
EINECS	Contact for details

Quality Control

Our (1S,6R)-1,3,3,6-Tetramethyl-2,3,5,6-Tetrahydro-1H-Indene-1,7-Dicarbaldehyde is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture and atmospheric oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.