Description

2-Benzyl-3-Formylpropanoic Acid is a versatile organic building block characterized by its benzyl-protected aldehyde and carboxylic acid functionalities. This compound matters as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and fine chemicals, enabling precise structural modifications. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of chiral drugs, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its reactive aldehyde group for constructing heterocyclic rings.
• Peptidomimetic Research: Acts as a scaffold for designing peptide analogs and enzyme inhibitors in medicinal chemistry programs.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Utilized in the multi-step synthesis of flavors, fragrances, and advanced polymer additives.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and chemical biology studies.

Basic Information

Product Name	2-Benzyl-3-Formylpropanoic Acid
CAS No.	96686-58-7
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	3-Formyl-2-benzylpropanoic Acid; 2-Benzyl-3-oxopropanoic Acid; 3-Benzyl-4-oxobutanoic Acid (tautomeric form); NSC 403119; (2-Benzyl-3-oxopropyl)formic Acid; β-Benzyl-β-formylpropionic Acid; 2-(Phenylmethyl)-3-oxopropanoic Acid; 3-Oxo-2-(phenylmethyl)propanoic Acid
EINECS	Contact for details

Quality Control

Our 2-Benzyl-3-Formylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.