Description

2-Acetamido-5,5,5-Trifluoropentanoic Acid is a high-purity, non-natural amino acid derivative characterized by its trifluoromethyl group, which imparts unique physicochemical properties critical for advanced research and development. This compound serves as a versatile and valuable building block in medicinal chemistry, enabling the synthesis of novel bioactive molecules with enhanced metabolic stability and lipophilicity. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of new therapeutic agents and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, neurology, and metabolic disease research.
• Peptide Modification: Used to incorporate fluorine atoms into peptide chains to enhance their stability, bioavailability, and binding affinity.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides and pesticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Fluorine Chemistry: An essential reagent in organofluorine chemistry for studying structure-activity relationships (SAR) and creating fluorinated analogs of biological compounds.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes and bioconjugates for diagnostic assays and biochemical research.
• Material Science: Potential application in the synthesis of advanced polymers and materials with specific surface properties.

Basic Information

Product Name	2-Acetamido-5,5,5-Trifluoropentanoic Acid
CAS No.	96563-56-3
Molecular Formula	C7H10F3NO3
Molecular Weight	213.16 g/mol
Synonyms	5,5,5-Trifluoro-N-acetyl-norvaline; N-Acetyl-5,5,5-trifluoronorvaline; 2-Acetylamino-5,5,5-trifluoropentanoic Acid; 2-(Acetylamino)-5,5,5-trifluoropentanoic Acid; N-Acetyl-5,5,5-trifluoronorvaline; 5,5,5-Trifluoronorvaline N-acetate; (RS)-2-Acetamido-5,5,5-trifluoropentanoic acid
EINECS	Contact for details

Quality Control

Our 2-Acetamido-5,5,5-Trifluoropentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.