Description

Bromofluoroacetonitrile is a versatile and highly reactive bifunctional building block containing both bromine and fluorine substituents on an acetonitrile backbone. This compound matters for its unique reactivity profile, enabling the efficient introduction of fluorinated nitrile groups into complex molecular architectures, which is critical for tuning the physical and biological properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key synthon for incorporating fluorinated nitrile moieties into drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Fluorine Chemistry Research: An essential reagent for studying nucleophilic substitution reactions and developing new fluorination methodologies.
• Ligand and Catalyst Development: Employed in the synthesis of complex, fluorinated ligands for catalytic systems.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	Bromofluoroacetonitrile
CAS No.	96449-14-8
Molecular Formula	C2HBrFN
Molecular Weight	137.93 g/mol
Synonyms	Bromo(fluoro)acetonitrile; Fluoro(bromo)acetonitrile; 2-Bromo-2-fluoroacetonitrile; Acetonitrile, bromofluoro-; Bromofluoro methane carbonitrile; (Bromofluoromethyl)carbonitrile; 96449-14-8 (CAS)
EINECS	Contact for details

Quality Control

Every batch of Bromofluoroacetonitrile is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C. Keep the container tightly sealed in a dry environment to minimize moisture ingress and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.