Description

1-Chloro-2-(3,3,3-Trifluoropropyl)Benzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a chlorinated benzene ring with a trifluoropropyl side chain, which is critical for modulating the physicochemical properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Employed in the research and development of organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions like Suzuki, Negishi, and Kumada couplings for constructing complex biaryl systems.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring the effects of fluorine introduction on molecular properties.

Basic Information

Product Name	1-Chloro-2-(3,3,3-Trifluoropropyl)Benzene
CAS No.	96256-38-1
Molecular Formula	C9H8ClF3
Molecular Weight	208.61 g/mol
Synonyms	2-Chloro-1-(3,3,3-trifluoropropyl)benzene; 1-Chloro-2-(3,3,3-trifluoropropyl)benzene; Benzene, 1-chloro-2-(3,3,3-trifluoropropyl)-; o-Chloro-(3,3,3-trifluoropropyl)benzene; 2-(3,3,3-Trifluoropropyl)chlorobenzene; (3,3,3-Trifluoropropyl)-2-chlorobenzene; 1-Chloro-2-(trifluoropropyl)benzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-(3,3,3-Trifluoropropyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications and results from techniques including GC, HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.3 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.